Egg donation as a route to get pregnant is potentially risky for women who suffer from Turner's syndrome.
Turner's syndrome
Turner's syndrome is a chromosomal disorder which affects approximately 1 in every 2500 women. The majority of women are born with two X chromosomes, but a woman with Turner's syndrome has only a single X chromosome, this can lead to a variety of health problems.
Turner's health problems
The health problems include an increased risk of heart disease, skeletal problems, and short stature, usually treated with growth hormone. Crucially women with Turner's syndrome are normally infertile.
Egg donation and pregnancy risks
Some women with Turner's syndrome have been able to have children by receiving and having donated eggs implanted. However, new research by the University of Nice in France now shows that this is a high-risk option.
Professor Patrick Fénichel led a study which looked at the results of Turner pregnancies in almost all the French clinics for assisted reproduction carrying out egg donation. The pregnancies of 93 mothers who had Turner's syndrome were monitored.
The research found that in 37.8% of pregnancies, mothers suffered from pregnancy-associated hypertensive disorders, including preeclampsia in 54.8% of cases, with 4 patients suffering severe eclampsia.
Baby health risks
Of the babies produced by Turner's syndrome mothers, 38.3% were born premature and 27.5% of the babies suffered from in-utero growth retardation. Two mothers died from rupture of the aorta after giving birth by caesarean section, and one foetal death was linked to eclampsia in the mother. Only 40% of pregnancies had a normal outcome for both the mother and child.
Read more at: news-medical.net
Turner's syndrome
Turner's syndrome is a chromosomal disorder which affects approximately 1 in every 2500 women. The majority of women are born with two X chromosomes, but a woman with Turner's syndrome has only a single X chromosome, this can lead to a variety of health problems.
Turner's health problems
The health problems include an increased risk of heart disease, skeletal problems, and short stature, usually treated with growth hormone. Crucially women with Turner's syndrome are normally infertile.
Egg donation and pregnancy risks
Some women with Turner's syndrome have been able to have children by receiving and having donated eggs implanted. However, new research by the University of Nice in France now shows that this is a high-risk option.
Professor Patrick Fénichel led a study which looked at the results of Turner pregnancies in almost all the French clinics for assisted reproduction carrying out egg donation. The pregnancies of 93 mothers who had Turner's syndrome were monitored.
The research found that in 37.8% of pregnancies, mothers suffered from pregnancy-associated hypertensive disorders, including preeclampsia in 54.8% of cases, with 4 patients suffering severe eclampsia.
Baby health risks
Of the babies produced by Turner's syndrome mothers, 38.3% were born premature and 27.5% of the babies suffered from in-utero growth retardation. Two mothers died from rupture of the aorta after giving birth by caesarean section, and one foetal death was linked to eclampsia in the mother. Only 40% of pregnancies had a normal outcome for both the mother and child.
Read more at: news-medical.net
